electromagnetic laminar jet break-up

ELECTROMAGNETIC LAMINAR JET BREAKUP

Specification

Particle size:

0.2 to 2 mm

Size distribution:

narrow (< 5%)

Volumetric flow:

1 to 50 ml/min per nozzle (multi nozzle systems available)

Particle production rate:

up to 2000 particles/s

Principle of technology

In the electromagnetic laminar jet breakup technique, a laminar jet of a precursor liquid passing a nozzle of appropriate diameter is broken into equally sized droplets by a superimposed mechanical vibration. The droplets are further processed into particles by crosslinking or polymerization (hardening process) of the precursor liquid. The hardening process must be very fast in order to achieve optimal particle quality. If no such fast hardening process is feasible (e.g. in cases where the hardening process is based on radical polymerization) the electromagnetic laminar jet breakup technology has to be combined with other technologies such as preenTec’s proprietary tandem process or a two phase system process. The electromagnetic laminar jet breakup technology gives a narrow bead size distribution. The particle diameter can be predicted and controlled by choosing the nozzle diameter, volumetric flow and superimposed frequency.Materials that can be processed
  • Alginate: hardened by crosslinking with bivalent metal ions; alginate particles can be further processed to result in coated particles as alginate-polylysine-alginate, alginate-polyethylenimine or multiply coated systems
  • Carrageenan: hardened by crosslinking with mono or bivalent metal ions and / or thermal gelation
  • Pectinate: hardened by crosslinking with trivalent metal ions
  • Agarose: hardened by thermal gelation
  • Cellulosesulfate: hardened by PDADMAC
  • Chitosan: hardened by crosslinking with polyphosphate
  • Acrylamide and other acrylic monomers: hardened by radical polymerization; combination with tandem process or two phase system is mandatory
  • Waxes and paraffin: hardened by thermal solidification
Application example
  • Microencapsulation, immobilization and stabilization of living cells (microbial or mammalian) for biocatalytic applications
  • Encapsulation and stabilization of food additives as vitamins, flavors or probiotic supplements
  • Oral pharmaceutical formulation
Microbeads made from sodium alginate with low size distribution (mean size 185 micrometer) produced by electromagnetic laminar jet breakup technology.

Microbeads made from sodium alginate with low size distribution (mean size 185 micrometer) produced by electromagnetic laminar jet breakup technology.

Microparticles made from sodium alginate (mean size 380 micrometers) containg bacterial colonies

Microparticles made from sodium alginate (mean size 380 micrometers) containg bacterial colonies